Drugs / Dexamethasone

Dexamethasone

Drug Approved in the United States; prescription-only

Fluorinated glucocorticoid corticosteroid·First approved·1958

Registered trials
2117
Ongoing
521/ 25%
Completed
1022
Indications
9

Approved indications

Indication
Rheumatic diseases
Severe allergies
Asthma
COPD
Croup
Brain swelling
Tuberculosis adjunctive use with antibiotics
Adrenocortical insufficiency (with mineralocorticoid)
Preterm labor fetal benefit

Clinical trial landscape

2117 registered studies reference this molecule or one of its brands. The split below shows how many are ongoing versus completed per phase.

Phase Total Ongoing Completed Split
Phase 2 680 182 317
Phase 3 423 111 212
Phase 4 279 53 141
Phase 1 244 43 136
Not applicable 199 44 103
Phase 1/2 193 60 75
Phase 2/3 51 16 18
Early Phase 1 25 6 9
Unknown 23 6 11
All phases 2117 521 1022

Ongoing Completed Balance withdrawn, terminated, or status unreported.

Study records: ClinicalTrials.gov →

Mechanism of action

Provides anti-inflammatory and immunosuppressive effects.

Recent developments