Drugs / Fentanyl

Fentanyl

Drug Approved in the United States

Synthetic opioid analgesic·First approved·1968

Registered trials
454
Ongoing
38/ 8%
Completed
280
Indications
5

Approved indications

Indication
Severe pain management in opioid-tolerant patients
"Analgesia before
during
and after surgery"
Anesthesia support (general or regional anesthesia)

Clinical trial landscape

454 registered studies reference this molecule or one of its brands. The split below shows how many are ongoing versus completed per phase.

Phase Total Ongoing Completed Split
Phase 4 157 16 91
Not applicable 142 9 76
Phase 3 45 3 32
Phase 2 36 2 28
Unknown 24 3 19
Phase 2/3 19 3 11
Phase 1 17 0 13
Phase 1/2 9 0 8
Early Phase 1 5 2 2
All phases 454 38 280

Ongoing Completed Balance withdrawn, terminated, or status unreported.

Study records: ClinicalTrials.gov →

Mechanism of action

Mu-selective opioid receptor agonist that produces analgesia via opioid receptor activation.

Recent developments