DrugEvidence

Diseases / Alopecia

Alopecia

Disease

Alopecia (hair loss) is loss of hair from part of the scalp or body and can range from small patches to diffuse or complete loss. Common forms include male/female pattern hair loss, alopecia areata, and telogen effluvium.

Trials
464
Recruiting
48
Completed
226
With results
62

Last revised

Pipeline

Phase by status

PhaseRecruitingNot yetBy invitationActiveCompletedTerminatedWithdrawnUnknownAvailableTotal
Early Phase 1 127112 14
Phase 1 112036 31
Phase 1/2 6318116 26
Phase 2 45552444 78
Phase 2/3 3131 8
Phase 3 7632514 46
Phase 4 12227 14
Not applicable 22123138791138 195
Unknown 63122242111 52

Trials started per year

2021
7
2022
36
2023
47
2024
47
2025
52
2026
38
2027
3

Conditions studied, by phase

ConditionEarly Phase 1Phase 1Phase 1/2Phase 2Phase 2/3Phase 3Phase 4Not applicableUnknownTotal
Alopecia 143126788461419552 464
Alopecia Areata 2211215157 36
Breast Neoplasms 11122 16
Hair Diseases 1115133 15
Alopecia universalis 71213 14
Skin Diseases 12212 8
Acne Vulgaris 2113 7
Lichen Planus 114 6
Autoimmune Diseases 14 5
COVID-19 13 4

Most active sponsors

#SponsorTrialsPhase 3
1Aderans Research Institute110
2Applied Biology, Inc.93
3Suzhou Kintor Pharmaceutical Inc,92
4Allergan70
5Cairo University71
6Ablon Skin Institute Research Center60
7Assiut University60
8NovoBliss Research Pvt Ltd60
9Pfizer63
10GlaxoSmithKline53

Most studied interventions

#InterventionTrials
1Minoxidil50
2Finasteride13
3Solutions13
4Sodium Chloride9
5Dutasteride7
6Dietary Supplements5
7Injections5
8Bimatoprost4
9Biotin4
10Low-Level Light Therapy4

Evidence

Results reported
27.4%62 of 226 completed
Published
5.8%13 of 226 completed
Primary endpoint met
72.5%29 of 40 analyses
Median months to report
15

Documents disclosed

Protocol available
45
Statistical analysis plan
40
PubMed citations
100

Trial profile

Median enrollment
50
Median duration
14months
Countries
51
Study sites
1580

Who is enrolled

Adults
463
Children
37
Older adults
273
Healthy volunteers
191

Median enrollment by phase

Early Phase 1
29
Phase 1
35
Phase 1/2
35
Phase 2
70
Phase 2/3
638
Phase 3
331
Phase 4
53
Not applicable
43
Unknown
90

Where trials run

United States
197
China
32
Spain
23
Egypt
22
Germany
22
South Korea
21
Australia
16
Canada
16
India
16
Taiwan
16

Busiest cities

#CityCountryTrials
1New YorkUnited States41
2MinneapolisUnited States21
3PortlandUnited States21
4HoustonUnited States20
5AustinUnited States19
6MiamiUnited States19
7BerlinGermany16
8BeijingChina15
9Los AngelesUnited States15
10SeoulSouth Korea15

Terminations

Terminated
22
Withdrawn
22
Stopped for recruitment
1.9%9 of 464 trials

Stated reasons

Other / unclear
23
Recruitment
9
Regulatory
4
COVID-19
3
Business decision
2
Lack of efficacy
1
Funding
1
Safety
1

Reasons are grouped from the sponsor's own wording with a rule-based classifier; the original text is shown below.

Recently stopped

TrialStatusStated reasonStopped
NCT02849470 Withdrawn Withdrawn Terminated by researchers without submission of patient admission to study. COVID complicated continuing search for qualified candidates 2028-07-31
NCT06932393 Terminated Terminated Per updated regulatory requirements, the site is ineligible to proceed. The clinical institution office has terminated the project. 2026-04-17
NCT05129254 Withdrawn Withdrawn Study not initiated. 2025-12-31
NCT06854575 Terminated Terminated Sponsor Business Decision 2025-09-15
NCT06560385 Terminated Terminated No enough subjects within the recruitment period 2025-08-18
NCT06497764 Withdrawn Withdrawn Departmental research administration decided to close the study as there had been no enrollment. No participants were screened or consented. 2025-07-01
NCT05426629 Withdrawn Withdrawn IRB closed 2025-04-21
NCT04882969 Withdrawn Withdrawn Changed Indication 2024-12-31
NCT06484881 Withdrawn Withdrawn Concern about formulation patent 2024-10-10
NCT04517864 Terminated Terminated For business reasons 2024-05-07

Trial records

Individual study records live on ClinicalTrials.gov. A sample of the trials counted above:

Search all Alopecia trials on ClinicalTrials.gov →